Fluvastatin for Prevention of Cardiac Events Following Successful First Percutaneous Coronary Intervention<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>
نویسندگان
چکیده
منابع مشابه
Fluvastatin for prevention of cardiac events following successful first percutaneous coronary intervention: a randomized controlled trial.
CONTEXT Percutaneous coronary intervention (PCI) is associated with excellent short-term improvements in ischemic symptoms, yet only three fifths of PCI patients at 5 years and one third of patients at 10 years remain free of major adverse cardiac events (MACE). OBJECTIVE To determine whether treatment with fluvastatin reduces MACE in patients who have undergone PCI. DESIGN AND SETTING Rand...
متن کاملCost-effectiveness of fluvastatin following successful first percutaneous coronary intervention.
BACKGROUND In the LIPS (Lescol Intervention Prevention Study), fluvastatin 80 mg/day reduced the risk of major adverse cardiac events (MACE) by 22% versus placebo (p = 0.01) following successful first percutaneous coronary intervention (PCI) in patients with stable or unstable angina or silent ischemia. The cost-effectiveness of such therapy is unknown. OBJECTIVE To evaluate the cost-effectiv...
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متن کاملFluvastatin reduced major adverse cardiac outcomes after first percutaneous coronary intervention.
P a t i e n t s 1677 patients 18 to 80 years of age (mean age 60 y, 84% men) who had completed a first PCI and had total cholesterol levels 3.5 to 7.0 mmol/L and fasting triglyceride levels < 4.5 mmol/L before the index procedure. Exclusion criteria were high blood pressure uncontrolled with treatment, left ventricular ejection fraction < 30%, previous PCI or coronary artery bypass grafting (CA...
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ژورنال
عنوان ژورنال: JAMA
سال: 2002
ISSN: 0098-7484
DOI: 10.1001/jama.287.24.3215